- Drugs that are administered by this route act less rapidly than those administered through intravenous route but the effect is long lasting.
- Aqueous or oily solutions or suspensions of drugs can be administered intramuscularly.
- The rate of absorption depends on the drug properties and formulations.
- Solutions are more rapidly absorbed than suspensions or oleaginous preparations.
- Intramuscular injections penetrate deep into the skeletal muscles. The point of injection should be away from the nerves and blood vessels.
- The point at which the needle enters and deposits the medication might experience injuries such as neural damage, abscess, cyst, embolism and sloughing of the skin to the patients.
- In adults gluteus maximus is the site for intramuscular injection, whereas in infants and young children, the deltoid muscles of the upper arm or the midlateral muscles of the thigh are the preferred sites for injection.
- The volume of medication administered may be a maximum of 5 ml in the gluteal region and 2 ml in the deltoid region.
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