This is a sponge-like mass of human fibrin. It is prepared by whipping a solution of fibrinogen into froth by mechanical means and then adding thrombin. The product is poured into trays and freeze-dried. Then, it is cut into pieces of convenient size and sterilized by dry heat at 130°C for three hours.

Storage: Human fibrin foam should be kept below 20°C and protected from light, moisture and oxygen. It need not be kept under nitrogen.

Uses: It is used with thrombin as a hemostat in surgery. A piece is dipped into thrombin solution and applied to the bleeding area. The combination of thrombin and the large rough surface provided by the sponge causes the blood to clot. The foam can be left in situ where it will be absorbed, because it is entirely of human origin.