1. It is a reversible inhibition.
2. In this type of inhibition, there is structurally similarity between the inhibitor and the substrate, and hence there is competition between I and S for the active site of the enzyme.
3. In this type, both ES and EI complexes are formed during the reaction.

Inhibitors for this enzymes are Figure 6.19:

Figure 6.19 Competitive Inhibitors for Succinic Dehydrogenase

However, the actual amount of ES and EI will depend on the following:.

1. Affinity between enzymes and substrate inhibitor.
2. Actual concentration of substrate and inhibitor present.

Thus, if I is present in sufficiently high concentration, it can replace the substrate entirely and thus block the reaction or lower the rate of the reaction.

Thus, K_m is high, but V_max is the same in competitive inhibitor.

However, when the concentration of [S] is increased, the effect of I can be reversed, forcing it out from EI complex; thus, [I] and [S] are mutually exclusive.