Plantlets from tissue culture give rise to morphological variation compared to the original source plants. These variations may be of economic importance, when desirable variants are suitably selected. This is especially valuable in plant-breeding programs in sexually reproducing crop plants with limited variability and to induce variation in vegetatively propagated species. Somaclonal variation has been successfully exploited in producing better variants of wheat, rice, maize, alfalfa, tomato, tobacco, sugarcane, cardamom and the like. In our country, variants of lemongrass, turmeric, ginger, cardamom, sugarcane, and mustard have been released. High yielding somaclonal variants of medicinal plants include those of C. roseus, Nicotiana rustica, Coptis japonica, Anchusa oficinalis, Lithospermum erythrorhizon, and Hyoscyamus muticus.