Sprays are the liquid preparations of medicaments in aqueous, alcoholic, or glycerin-containing vehicle and are meant for application to the nose or throat by means of an atomizer or nebulizer. Coarse droplets of the medicaments will be administered to the upper respiratory tract, whereas very fine droplets penetrate into the respiratory tract. Aqueous sprays that are isotonic with nasal secretions and are of the same pH are preferred. Sprays usually contain medicaments such as antibiotics, antihistaminics, and vasoconstrictors.