There is a continuous transport of amino acids from muscle to liver, which predominantly occurs during starvation. Alanine dominates among the amino acids. It is postulated that pyruvate in skeletal muscle undergoes transamination to produce alanine. Alanine is transported to liver and used for gluconeogenesis. This cycle is referred to as Glucose Alanine Cycle (Figure 8.28).

Figure 8.28 The Cori Cycle or (Glucose Alanine Cycle)