Antitussive Formulation

These are the drugs that act in the central nervous system (CMS) to raise the threshold of cough center or act peripherally in the respiratory tract to reduce tussal impulses or to perform both these actions.

Formula

Adhatoda vasaka1.5%
Glycyrrhiza glabra1.5%
Acorus calamus0.1%
Alpinia galangal0.1%
Zingiber officinale0.1%
Sucrose66.7%
Alcohol (10%)50%
Water (q.s.)100 ml

Preparation

Adhatoda vasaka, Glycyrrhiza glabra, Acorus calamus, Alpinia galangal and Zingiber officinale are collected and dried in shade. The dried materials are then powdered and extracted with 50% aqueous alcohol for five days. At the end of this process, the solvent is decanted and filtered if necessary to remove the plant debris. The extract is then concentrated under vacuum at temperature less than 50°C and lyophilized to obtain the extract in the powder form.

The plant extracts are dissolved in 50 ml of 10% alcohol, filtered and a specified quantity of sucrose is added. The preparation is heated gently with continuous stirring until sucrose is dissolved and then the volume is made with required amount of water.


Leave a Reply

Your email address will not be published. Required fields are marked *