Answer in Detail
Controlled release refers to the release of drug into a patient’s body at a predetermined rate, at specific times, or with specific release profiles. Its advantages are reduction of dosing frequency, reduction in the fluctuation in circulating drug levels, increase in patient compliance, uniform effect, and reduction in GI irritation and other dose-related side effects.…
Implants are sterile small tablets meant for insertion under the skin by making a small incision beneath the skin, which is stitched later. Implants are about 3.2 mm in diameter and 8 mm in length and prepared by compression. They are implanted subcutaneously for the purpose of providing slow and continuous release of medication over…
Aerosols are defined as pressurized package disperse phase systems in which solid particles or liquid droplets constitute the disperse phase and gas (propellant) the continuous phase. Compressed gases, such as carbon dioxide and nitrogen, and liquefied gases such as halogen derivative of some saturated hydrocarbons (methane, ethane, propane, etc.) can be used as propellants. The material…
These are aqueous solutions of drops that are instilled into the nose with a dropper. Oily vehicle is not preferable because it will inhibit the movement of cilia in the nasal mucosa. Nasal drops should be isotonic, should have neutral pH and viscosity similar to nasal secretions. This can be achieved by using 0.9% sodium…