Creams are viscous emulsions or semisolid preparations consisting of solutions or dispersions of one or more medicaments in suitable base and are intended for application to the skin or mucous membrane. Creams are applied for protective, beautifying, therapeutic, or prophylactic purposes. They contain suitable antimicrobial preservatives to have sufficient intrinsic bactericidal and fungicidal activity. Creams are mainly of two types, namely water-in-oil (w/o) and oil-in-water (o/w) types. Sometimes, dilutions of proprietary creams are required. They can also be used after dilution. For this, an appropriate diluting agent should be used and heating should be avoided. Such diluted creams should be used within two weeks of their preparation.