The removal of amino group from the amino acid as NH3 is termed as deamination. Transamination involves only the shuffling of amino groups among the amino acids. On the other hand, deamination results in the liberation of ammonia for urea synthesis. These reactions occur primarily in liver and kidney and provide α-keto acid (which can enter the central pathway of energy metabolism). Deamination may be oxidative or non-oxidative.
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