Learning Objective

• Classification and process of sterilization methods

The process of sterilization signifies a complete removal of all living microorganisms from the preparation. It also indicates the killing of all living, micro-organisms including their spores. The common methods of sterilization of pharmaceuticals are as follows:

1. Moist heat sterilization
2. Dry heat sterilization
3. Filtration sterilization
4. Gas sterilization
5. Ionizing radiation sterilization

Depending upon the nature of the pharmaceutical preparation, a suitable method of sterilization is selected.