Ointments are semisolid preparations for application to the skin or mucous membranes. They are often anhydrous and contain the medicament either dissolved or dispersed in the vehicle. The solid substances that are dispersed should be in the form of a micronized powder. Ointments are easily spreadable and their plastic viscosity may be controlled by modifications of the formulation. They are typically used as emollients, protective barriers, and vehicles to incorporate medicaments. Ointment bases are mainly of four types, namely hydrocarbon or oleaginous base, absorption base, emulsifying base, and water-soluble base. They are prepared by trituration, fusion, or chemical reaction method.