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  • Angiotensin

    August 7, 2024
    Amino Acids

    Angiotensin 1 is a decapeptide (ten amino acids), which is converted to angiotensin 2 (eight amino acids). The latter has more hypertensive effect and also stimulates the release of aldosterone from adrenal gland. Methionine enkephalin is a pentapeptide found in brain. Functions: It has opiate-like function and inhibits the sense of pain. Bradykinin and kallidin are…

  • Vasopressin (Antidiuretic Hormone (ADH)):

    August 7, 2024
    Amino Acids

    ADH is also a nanopeptide produced by posterior pituitary gland. Functions: It stimulates the kidney to retain water and thus increases blood pressure.

  • Oxytocin

    August 7, 2024
    Amino Acids

    It’s a hormone secreted by posterior pituitary gland and contains nine amino acids (nanopeptide). Functions: It stimulates the contraction of smooth muscles, especially during childbirth.

  • Methods of Manufacture of Ointments

    August 7, 2024
    Semisolid Dosage Forms

    The following are the various methods of manufacturing ointments:

  • Thyrotropin Releasing Hormone (TRH)

    August 7, 2024
    Amino Acids

    It is a tripeptide secreted by hypothalamus.   —OOc—Glu—His—Pro—NH2 Functions: It stimulates pituitary gland to release thyrotropic hormone.

  • Functions of glutathione

    August 7, 2024
    Amino Acids

    The reversible oxidation–reduction of glutathione is important for many of its biological functions. It maintains a ratio of about 10011 of GSH to G—S—S—G. Glutathione (reduced) performs specialised functions in erythrocytes. It maintains RBC membrane structure in integrity. It protects haemoglobin from getting oxidised by agents such as H2O2. It involves in the transport of…

  • Glutathione

    August 7, 2024
    Amino Acids

    It is a tripeptide composed of three amino acids. Chemically, glutathione is γ—glutamyl—cysteine—glycine. It is widely distributed in nature and exists in reduced or oxidised states. Structure of glutathione is as given below:

  • Classification of Ointment Bases

    August 7, 2024
    Semisolid Dosage Forms

    Ointment bases are classified into the following categories: Oleaginous (Hydrocarbon) bases: These bases consist of oils and fats and, hence, are hydrophobic in nature, with the least water absorption capacity. Oleaginous bases provide emollient and protective properties by restricting the loss of moisture from the skin and remaining on the skin for prolonged periods. They are…

  • BIOLOGICALLY IMPORTANT PEPTIDES

    August 7, 2024
    Amino Acids

    Several peptides occur in the living organisms that display a wide spectrum of biological functions.

  • Ointment Base

    August 7, 2024
    Semisolid Dosage Forms

    The ointment base is an integral part of an ointment preparation and serves as a carrier or vehicle for the medicament. Ideal Properties of a Base

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