Learning Objective
- Definition of tablet coating and their types
- Need for tablet coating and its methodology
It is a process of application of coating material onto the external surface of the core tablet. The tablets are coated for the following reasons:
- To increase aesthetic appeal of the product
- To mask the unpleasant taste of the drug
- To protect the drug release in the gastric environment of the stomach with an acid resistant enteric coating material
- To control or delay the release of the drug for a longer period of time
- To incorporate another drug in coating
- To avoid chemical incompatibility
- To protect the drug from environmental decomposition
Requirements of an uncoated tablet to undergo coating procedure are as follows:
- The tablet should possess optimum convexity to overcome the problem of edge coverage of the coat.
- The tablet should be hard enough to withstand the rigors of coating procedure.
- Tablets should have minimum tendency to absorb the solvent deep into the coat.
- Friability value of the tablets should be minimum.
- Tablets should disintegrate immediately once coating has dissolved.
- Uncoated tablets should be in a position to subject itself to dedusting procedures. Otherwise it may impart roughness on the coated tablets.
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