- Wetting agents will facilitate the dispersion of drug in the vehicle, especially in case of aqueous suspensions.
- It reduces the contact angle between the surface of the particle and the vehicle.
- Surfactants with a hydrophilic lipophilic balance (HLB) value between 7 and 9 will serve as effective wetting agents.
- The usual concentration of wetting agent is 0.05% – 0.5%.
- Use of excess quantity may cause foaming and caking and may impart undesirable odor to the formulation.
Leave a Reply